Mutation-free expression of c-Kit proto-oncogene in primary adenocarcinoma of uterine cervix.
نویسندگان
چکیده
a Institute of Medicine, Chung-Shan Medical University, Taichung, Taiwan b Department of Pathology, Chung-Shan Medical University and Chung Shan Medical University Hospital, Taichung, Taiwan c Department of Pathology, Laboratory Medicine and Department of Medicine, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan d Postgraduate Year Program, Chung-Shan Medical University and Chung-Shan Medical University Hospital, Taichung, Taiwan e Department of Obstetrics and Gynecology, Clinical Trial Center, Chung Shan Medical University Hospital, Taichung, Taiwan
منابع مشابه
A promising hypothesis of c-KIT methylation/ expression paradox in c-KIT (+) squamous cell carcinoma of uterine cervix ----- CTCF transcriptional repressor regulates c-KIT proto-oncogene expression
We recently reported one interesting case showing mutation-free c-KIT proto-oncogene overexpression and paradoxical hypermethylation in 54 cases of primary squamous cell carcinoma of uterine cervix (SCC). However, its molecular mechanisms still remain unknown. We propose the hypothesis that increased methylation at the CpG islands on the promoter near the first exon region might interfere with ...
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ورودعنوان ژورنال:
- Taiwanese journal of obstetrics & gynecology
دوره 55 5 شماره
صفحات -
تاریخ انتشار 2016